The human digestive system contains a vast world of bacteria and fungi (the gut microbiome), which greatly influence metabolism, body weight, the immune system, appetite and mood.
New research has discovered the ability of the “gut microbiome” to predict obesity, as its genes and differences in functional appearance are linked to the body’s response to weight loss, as stated by “Medical News Today”.
Some experts believe that the “gut microbiome” significantly affects metabolism, immune function and mental health, as well as affecting energy metabolism by regulating glucose metabolism, appetite and fat storage, and some studies have shown that changes in the composition and function of gut microbiota are associated with obesity and disease. diabetes mellitus;
By identifying the most abundant genes in the gut microbiome and the biological function these genes perform, researchers at the Institute of Systems Biology in Seattle inferred the functional profile of the entire gut microbiome. A person’s ability to lose weight.
Previous studies have distinguished between individuals who have lost weight and those who are resistant to losing weight, as there was a difference in the abundance of microbiome genes that affect human metabolism, while the lead author of the new study, Dr. Individuals’ response to a moderate lifestyle or to more stringent weight loss interventions.
Dr. Gibbons added that new research points to the organisms and genes responsible for successful weight loss, which may guide future interventions and research aimed at engineering weight loss-resistant microbiomes into microbiomes that allow weight loss.
In this study, researchers analyzed data from 105 individuals, including their weight and body mass index (a person’s height and weight to estimate their percentage of body fat). Composition and function of the gut microbiota. When examining data from all participants, the researchers found that individuals with a higher BMI initially lost more weight.
The researchers also assessed differences in gut microbiota function using metagenomic analysis, which involves identifying the most abundant genes in the community of microorganisms that make up the gut microbiota.