Japanese scientists develop vaccine to kill ‘zombie cells’

Japanese scientists published in the journal “Nature Aging” a research paper describing a vaccine to destroy the so-called “zombie cells” that destroy nearby cells.
These cells are thought to be responsible for age-related diseases such as atherosclerosis and osteoporosis.
The vaccine has been shown to be effective in mice. Non-metastatic glycoprotein B (GPNMB) has been identified as a target for treatment with a new vaccine. Scientists have created an amino acid-based peptide vaccine. The vaccine produces antibodies that eventually destroy senescent cells and clear blockages in the blood vessels. The lifespan of the mice increased, the degree of arteriosclerosis decreased, and their metabolism improved.
Research has shown that Gpnmb vaccination may be a potential strategy for new age-related therapies, particularly for the treatment of metabolic dysfunction and atherosclerosis.